Using a mouthwash probiotic can be an effective adjunctive therapy to treat periodontal disease. Periodontitis is an inflammation of the gums that can lead to bone loss and tooth loss. Periodontitis is associated with increased risks of developing diabetes and heart disease. The oral microbiome is an important part of the digestive system. It contains trillions of microbes. They are essential for your overall health and connect to other parts of the body.